상위피인용논문
- 조회337
University of Idaho
Ji Youn Lim,1 Jang W. Yoon,2 and Carolyn J. Hovde1,*
1 Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, Idaho 83844, U.S.A
2 Advanced Human Resource and Research Group for Medical Science (BK21), Konkuk University School of Medicine, Seoul 143-701, Korea
*Corresponding author: Carolyn J. Hovde
Abstract
Enterohemorrhagic Escherichia coli O157:H7 is a major foodborne pathogen causing severe disease in humans worldwide. Healthy cattle are a reservoir of E. coli O157:H7, and bovine food products and fresh produce contaminated with bovine waste are the most common sources for disease outbreaks in the United States. E. coli O157:H7 also survives well in the environment. The abilities to cause human disease, colonize the bovine gastrointestinal tract, and survive in the environment require that E. coli O157:H7 adapt to a wide variety of conditions. Three major virulence factors of E. coli O157:H7 have been identified including Shiga toxins, products of the pathogenicity island called the locus of enterocyte effacement, and products of the F-like plasmid pO157. Among these virulence factors, the role of pO157 is least understood. This review provides a board overview of E. coli O157:H7 with an emphasis on pO157.
Keywords: E. coli O157:H7, pO157
논문정보
- Review Paper
- 2010년 01월 (BRIC 등록일 2019-04-05)
- 국내+국외 연구진
- 120회 이상 인용된 논문
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