한빛사논문
- 조회1,440
Minsoo Kim, MD1, Chan-Hyung Kim, MD, PhD3, Hyun Ho Jung, MD, PhD2, Se Joo Kim, MD, PhD3, Jin Woo Chang, MD, PhD2,*
1 Department of Neurosurgery, Catholic University of Korea Incheon St. Mary’s Hospital, Incheon, Korea
2 Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea
3 Department of Psychiatry, Yonsei University College of Medicine, Seoul, Korea
*Corresponding author: Jin Woo Chang, MD, PhD, Division of Stereotactic and Functional Neurosurgery, Department of Neurosurgery, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea.
Abstract
Treatment-resistant major depressive disorder (MDD) has been associated with high rates of suicide and severe disability, prompting the introduction of invasive interventions for the management of affected patients 1; 2; 3; 4 ; 5. Magnetic resonance?guided focused ultrasound surgery (MRgFUS) has gained popularity as a minimally invasive thermal lesioning technique for the management of various diseases such as essential tremor, obsessive compulsive disorder (6), and Parkinson’s disease 7 ; 8. The present report discusses the case of a patient who exhibited dramatic improvement in depressive symptoms following bilateral anterior capsulotomy via MRgFUS, despite the failure of various psychotherapies, medications, and electroconvulsive therapy prior to MRgFUS. This was a single-center observational study without controls. Study details can be found at ClinicalTrials.gov (Registration: NTC02348411).
Keywords : Depressive disorder; treatment-resistant; Magnetic resonance imaging; interventional; High-intensity focused ultrasound ablation; Internal capsule; Anterior capsulotomy; Psychosurgery
논문정보
- Correspondence
- 2017년 05월 (BRIC 등록일 2017-05-18)
- 국내 연구진
- 의약학 > 응용의학
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