박경민 (기초과학연구원, UST)

한빛사논문

조회1,625

기초과학연구원, UST

CV File 312 kb

Acc. Chem. Res., Publication Date (Web): March 21, 2017 | DOI: 10.1021/acs.accounts.6b00645 [Commentarty]Ultrastable Artificial Binding Pairs as a Supramolecular Latching System: A Next Generation Chemical Tool for Proteomics

Abstract

Kyeng Min Park^†§⊥, James Murray^†⊥, and Kimoon Kim^*†‡^† Center for Self-assembly and Complexity (CSC), Institute for Basic Science (IBS), Pohang 37673, Republic of Korea
^‡Department of Chemistry, Pohang University of Science and Technology, Pohang 37673, Republic of Korea
^§Department of Nanomaterials and Engineering, University of Science and Technology (UST), Daejon 34113, Republic of Korea

^*Corresponding Author

Author Contributions
^⊥K. M. P. and J. M. contributed equally.

Abstract
In this Commentary, we discuss cucurbit[7]uril-based ultrastable artificial binding pairs as a supramolecular latching system and how we envision this becoming important tools in proteomics. The limitations of current proteomic techniques are described with an emphasis on the lack of tools to answer questions about the complex and dynamic nature of the proteome. Our thoughts as to how artificial ultrastable binding pairs may be able to address these questions are given especially when they are combined with existing methods.

논문정보

형식Commentarty
게재일2017년 03월 (BRIC 등록일 2017-03-24)
연구진국내 연구진
분야 바이오·의료융합 > 바이오센싱 및 나노바이오물질

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