한빛사논문
- 조회2,987
Abstract
Yoosoo Yang1,*, Yeonsun Hong1,2, Gi-Hoon Nam1,2, Jin Hwa Chung3, Eunee Koh1,2 and In-San Kim1,2,*
1 Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea
2 KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, Republic of Korea
3 Bio-Imaging Center, Asan Institute for Life Science, Asan Medical Center, Seoul, Republic of Korea
*Corresponding authors
Abstract
An efficient system for direct delivery of integral membrane proteins is successfully developed using a new biocompatible exosome-based platform. Fusogenic exosomes harboring viral fusogen, vascular stomatitis virus (VSV)-G protein, can fuse with and modify plasma membranes in a process called “membrane editing.” This can facilitate the transfer of biologically active membrane proteins into the target cell membranes both in vitro and in vivo.
Keywords : exosomes; membrane protein; nanoplatform; viral fusogen
논문정보
- Research article
- 2017년 02월 (BRIC 등록일 2017-02-28)
- 국내 연구진
- 바이오·의료융합 > 바이오센싱 및 나노바이오물질
댓글 작성 로그인
팝업 닫기관련 링크
연구자 키워드
연구자 ID
관련분야 연구자보기
관련분야 논문보기
해당논문 저자보기
