구.농수식품
- 조회1,249
Abstract
Hye-Min Kanga, Chang-Bum Jeonga, b, Young Hwan Leea, Yan-Hong Cuic, Duck-Hyun Kima, Min-Chul Leea, Hui-Su Kima Jeonghoon Hana, Dae-Sik Hwanga, Su-Jae Leec, Jae-Seong Leea
a Department of Biological Science, College of Science, Sungkyunkwan University, Suwon 16419, South Korea
b Department of Chemistry, College of Natural Sciences, Hanyang University, Seoul 04763, South Korea
c Department of Life Sciences, College of Natural Sciences, Hanyang University, Seoul 04763, South Korea
Corresponding author : Jae-Seong Lee
Abstract
The mitogen-activated protein kinases (MAPKs) family is known to mediate various biological processes in response to diverse environmental pollutants. Although MAPKs are well characterized and studied in vertebrates, in invertebrates the cross-reactivities of MAPKs antibodies were not clearly known in response to environmental pollutants due to limited information of antibody epitopes with material resources for invertebrates. In this paper, we performed phylogenetic analysis of MAPKs genes in the marine rotifer Brachionus koreanus and the copepods Paracyclopina nana and Tigriopus japonicus. Also in rotifer and copepods, several studies of Western blot of MAPK signaling pathways were shown in response to environmental pollutants, including multi-walled carbon nanotubes (MWCNTs), water-accommodated fractions (WAFs) of crude oil, and microplastics. This paper will provide a better understanding of the underlying mechanistic scenario in terms of cross-reactivities of mammalian antibodies in rotifer and copepod.
Keywords : MAPKs; Rotifer; Copepod; Ecotoxicology; Signal transduction
논문정보
- Research article
- 2016년 12월 (BRIC 등록일 2017-02-02)
- 국내 연구진
- 생명과학 > 분류/생태/환경생물학
- 구・농수식품
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