구.농수식품
- 조회1,201
Abstract
Young Hwan Leea, 1, Hye-Min Kanga, 1, Duck-Hyun Kima, Minghua Wangb, Chang-Bum Jeonga, c,*, Jae-Seong Leea,*
a Department of Biological Science, College of Science, Sungkyunkwan University, Suwon, 16419, South Korea
b Center for Marine Environmental Chemistry and Toxicology, College of the Environment & Ecology, Xiamen University, Xiamen, 361102, China
c Department of Chemistry, College of Natural Sciences, Hanyang University, Seoul, 04763, South Korea
*Corresponding authors
1These authors contributed equally to this work.
Abstract
Methylmercury (MeHg) is a concerning environmental pollutant that bioaccumulates and biomagnifies in the aquatic food web. However, the effects of MeHg on marine zooplankton are poorly understood even though zooplankton are considered key mediators of the bioaccumulation and biomagnification of MeHg in high-trophic marine organisms. Here, the toxicity of MeHg in the benthic copepod Tigriopus japonicus was assessed, and its adverse effects on growth rate and reproduction were demonstrated. Antioxidant enzymatic activities were increased in the presence of MeHg, indicating that these enzymes play an important role in the defense response to MeHg, which is regulated by a complex mechanism. Subsequent activation of different patterns of mitogen-activated protein kinase (MAPK) pathways was demonstrated, providing a mechanistic approach to understand the signaling pathways involved in the effects of MeHg. Our results provide valuable information for understanding the toxicity of MeHg and the underlying defense mechanism in response to MeHg exposure in marine zooplankton.
Keywords : MeHg; Methyl mercury; Reactive oxygen species; Copepod; Tigriopus japonicus; Antioxidant system; MAPK signaling pathway
논문정보
- Research article
- 2017년 01월 (BRIC 등록일 2017-01-25)
- 국내(교신)+국외 연구진
- 생명과학 > 분류/생태/환경생물학
- 구・농수식품
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