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Abstract
Hee-Yong Kim
National Institute on Alcohol Abuse and Alcoholism, the National Institutes of Health, Bethesda, Maryland, USA.
Lysophosphatidylserines (lyso-PSs) are an emerging class of signaling lipids implicated in human inflammatory and autoimmune diseases. A newly discovered phosphatidylserine-specific lipase, ABHD16A, together with the recently described lyso-PS lipase ABHD12 shed light on the in vivo regulation of lyso-PS, providing a potential enzymatic target for modulating neuroinflammatory responses.
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