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손예준Yejun Son
경희대학교
Am. J. Psychiat., Jul 08 2026, | https://doi.org/10.1176/appi.ajp.20250944
Global Prevalence of Obsessive-Compulsive and Related Disorders: A Systematic Review and Modeling Study
Yi Deun Jeong 1,2, Yejun Son 2,3, Sangeon Jeon 4, Hanseul Cho 5, Seung Woo Ryuk 6, Yeona Jo 2,3, Guillaume Fond 7, Laurent Boyer 7, Lee Smith 8,9, Samuele Cortese 10,11,12,13,14, Paolo Fusar-Poli 15,16,17, Dong Keon Yon 1,2,3,18, Marco Solmi 19,20,21,22,23
1Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.
2Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
3Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.
4School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta.
5Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston.
6Department of Medicine, Ajou University School of Medicine, Suwon, South Korea.
7CEReSS-Health Service Research and Quality of Life Center, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France.
8Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK.
9Department of Public Health, Faculty of Medicine, Biruni University, Istanbul, Turkey.
10Developmental EPI (Evidence Synthesis, Prediction, Implementation) Lab, Centre for Innovation in Mental Health, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
11Hampshire and Isle of Wight NHS Foundation Trust, Southampton, UK.
12Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK.
13Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York.
14Department of Precision and Regenerative Medicine-Jonic Area, University of Bari Aldo Moro, Bari, Italy.
15Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
16OASIS Service, South London and Maudsley NHS Foundation Trust, London.
17Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London.
18Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.
19Department of Psychiatry, University of Ottawa, Ottawa.
20SCIENCES Lab, Department of Mental Health, Ottawa Hospital, Ottawa.
21Ottawa Hospital Research Institute, University of Ottawa, Ottawa.
22School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa.
23Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin.
Dr. Jeong, Mr. Son, and Mr. Jeon contributed equally as first authors.
Send correspondence to Dr. Yon
1Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.
2Center for Digital Health, Medical Science Research Institute, Kyung Hee University College of Medicine, Seoul, South Korea.
3Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.
4School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta.
5Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston.
6Department of Medicine, Ajou University School of Medicine, Suwon, South Korea.
7CEReSS-Health Service Research and Quality of Life Center, Assistance Publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France.
8Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK.
9Department of Public Health, Faculty of Medicine, Biruni University, Istanbul, Turkey.
10Developmental EPI (Evidence Synthesis, Prediction, Implementation) Lab, Centre for Innovation in Mental Health, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
11Hampshire and Isle of Wight NHS Foundation Trust, Southampton, UK.
12Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK.
13Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York.
14Department of Precision and Regenerative Medicine-Jonic Area, University of Bari Aldo Moro, Bari, Italy.
15Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
16OASIS Service, South London and Maudsley NHS Foundation Trust, London.
17Early Psychosis: Interventions and Clinical-Detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London.
18Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.
19Department of Psychiatry, University of Ottawa, Ottawa.
20SCIENCES Lab, Department of Mental Health, Ottawa Hospital, Ottawa.
21Ottawa Hospital Research Institute, University of Ottawa, Ottawa.
22School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa.
23Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin.
Dr. Jeong, Mr. Son, and Mr. Jeon contributed equally as first authors.
Send correspondence to Dr. Yon
Abstract
Objective: Obsessive-compulsive disorder (OCD) is one of the common mental disorders globally. However, there are limited studies on the prevalence of OCD and four other disorders categorized under obsessive-compulsive and related disorders, namely, hoarding disorder, excoriation disorder, body dysmorphic disorder, and trichotillomania. The authors sought to fill the epidemiological gap in the literature.
Methods: PubMed/MEDLINE, Embase, CINAHL, PsycINFO, and Google Scholar were systematically searched from inception to June 8, 2025. Studies representative of national or subnational general populations, with diagnoses based on DSM or ICD-10 criteria, were included. A Bayesian hierarchical linear mixed model was used to estimate the lifetime prevalence of OCD at the global, regional, and national levels, with estimates reported with 95% credible intervals. The authors examined the association between OCD prevalence and the Socio-demographic Index (SDI), and estimated age-specific point prevalence of OCD.
Results: A total of 112 studies reporting prevalence rates for obsessive-compulsive and related disorders were included. The global lifetime Bayesian prevalence of OCD across all ages was estimated at 2.57% according to ICD-10 criteria, 3.10% according to DSM-III criteria, 2.28% according to DSM-IV criteria, and 3.21% according to DSM-5 criteria. Lifetime prevalence of OCD was negatively correlated with SDI, indicating lower prevalence estimates in countries with higher SDI. The age-specific prevalence of OCD increased sharply in the teen years and peaked in the late 20s to early 30s. Point prevalence ranged across studies from 0.98% to 5.81% for hoarding disorder, from 2.33% to 7.68% for excoriation disorder, from 0.44% to 15.21% for body dysmorphic disorder, and from 0.0% to 2.12% for trichotillomania.
Conclusions: This study estimated the global prevalence of OCD according to diagnostic criteria, underscoring the role of diagnostic definitions in shaping epidemiological understanding.
Methods: PubMed/MEDLINE, Embase, CINAHL, PsycINFO, and Google Scholar were systematically searched from inception to June 8, 2025. Studies representative of national or subnational general populations, with diagnoses based on DSM or ICD-10 criteria, were included. A Bayesian hierarchical linear mixed model was used to estimate the lifetime prevalence of OCD at the global, regional, and national levels, with estimates reported with 95% credible intervals. The authors examined the association between OCD prevalence and the Socio-demographic Index (SDI), and estimated age-specific point prevalence of OCD.
Results: A total of 112 studies reporting prevalence rates for obsessive-compulsive and related disorders were included. The global lifetime Bayesian prevalence of OCD across all ages was estimated at 2.57% according to ICD-10 criteria, 3.10% according to DSM-III criteria, 2.28% according to DSM-IV criteria, and 3.21% according to DSM-5 criteria. Lifetime prevalence of OCD was negatively correlated with SDI, indicating lower prevalence estimates in countries with higher SDI. The age-specific prevalence of OCD increased sharply in the teen years and peaked in the late 20s to early 30s. Point prevalence ranged across studies from 0.98% to 5.81% for hoarding disorder, from 2.33% to 7.68% for excoriation disorder, from 0.44% to 15.21% for body dysmorphic disorder, and from 0.0% to 2.12% for trichotillomania.
Conclusions: This study estimated the global prevalence of OCD according to diagnostic criteria, underscoring the role of diagnostic definitions in shaping epidemiological understanding.
논문정보
- Research article
- 2026년 07월 (BRIC 등록일 2026-07-09)
- 국내(교신)+국외 연구진
- 의약학 > 의약학 기타
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