Effective bone tissue engineering strategies require scaffolds with tailored properties to address specific bone abnormalities and fractures. Herein, porous biocomposite scaffolds were fabricated via repeated freeze-casting and three-layer coating. The prepared system consisted of spray-dried β-TCP granules and bio-macromolecule gelatin-based soya protein isolate (S) combined with a layer of the biomimetic adherent poly-dopamine (PDA) for simvastatin (SIM) coating via dopamine self-polymerization through the dip-coating process. Thrombin (Th) was then loaded to make the final hemostatic hybrid bone graft (TGS/SIM/Th). The PDA adhered layer improved the mechanical qualities as expected (13.93 MPa). Additionally, MC3T3-E1 cell migration (>90%) and osteogenic differentiation (***p < 0.001) were superior in vitro. The sustained release of SIM (∼78%) can help form new capillary networks, and the burst release of Th (∼97.2%) supports the creation of stable blood coagulation. The hemostatic time of the TGS/SIM/Th significantly decreased (****p < 0.0001) in the critical-sized rat calvarial defect model and tail amputation model, which would effectively enhance the bone repair. This study shows that the fabricated biocomposite could represent a new approach for treating bone defects while absorbing a large amount of blood from onsite bleeding.