SiPore21 is an oral gel containing engineered mesoporous silica particles. These particles are micron-sized and tailored to have pores with a specific diameter, which are slightly larger than the size of digestive enzymes but smaller than undigested food. Owing to this unique physical structure and the consequent diffusion of enzymes into the pores, SiPore21 functions as a molecular sieve that physically separates digestive enzymes from undigested or partially digested food in the gastrointestinal tract. This physical separation reduces the enzymatic breakdown of carbohydrates and fats, thereby lowering nutrient absorption.
EClinicalMedicine2026-08-06
