Our study centers on hepatocellular carcinoma, which is the most prevalent form of liver cancer, ranking as the sixth most common and third most lethal cancer globally. Despite advancements in treatment modalities, the prognosis of HCC remains bleak due to its heterogeneity. Hence, we aimed to develop a novel gene set and AI tool to identify malignant hepatocytes in scRNA-seq data, thereby addressing the lack of existing biomarkers and computational tools and contributing to the discovery of therapeutic targets.
J. Big Data2024-10-30
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