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최종업데이트 2026.06.01.

A Prodrug Approach for Activity-Based Chemical Modulation toward Multiple Pathological Targets in Alzheimer's Disease
- Small, May 31 2026, | https://doi.org/10.1002/smll.74013
- 2026-05
- 바이오·의료융합
- 한빛사논문
Positional Isomerism Tunes Molecular Reactivities and Mechanisms toward Pathological Targets in Dementia
- J. Am. Chem. Soc., Dec 21 2025, | https://doi.org/10.1021/jacs.5c14323
- 2025-12
- 생명과학
- 한빛사논문
Disease-disease interactions: molecular links of neurodegenerative diseases with cancer, viral infections, and type 2 diabetes
- Transl. Neurodegener., Oct 17 2025, 14 (1) 52 | https://doi.org/10.1186/s40035-025-00507-3
- 2025-10
- 한빛사논문
Interactions with tau's microtubule-binding repeats modulate amyloid-β aggregation and toxicity
- Nat. Chem. Biol., Aug 22 2025, | https://doi.org/10.1038/s41589-025-01987-0
- 2025-08
- 생명과학
- 한빛사논문
- 임미희(KAIST)
Transition Metal Complexes as Therapeutics: A New Frontier in Combatting Neurodegenerative Disorders through Protein Aggregation Modulation
- Adv. Healthc. Mater., Sep 02 2024, | https://doi.org/10.1002/adhm.202401991
- 2024-09
- 생명과학
- 한빛사논문
APP-C31: An Intracellular Promoter of Both Metal-Free and Metal-Bound Amyloid-β40 Aggregation and Toxicity in Alzheimer's Disease
- Adv. Sci., Nov 10 2023, | https://doi.org/10.1002/advs.202307182
- 2023-11
- 생명과학
- 한빛사논문
Conformational and functional changes of the native neuropeptide somatostatin occur in the presence of copper and amyloid-β
- Nat. Chem., 2022 Sep;14(9):1021-1030 | doi: 10.1038/s41557-022-00984-3
- 2022-09
- 생명과학
- 한빛사논문
Mechanistic Insight into the Design of Chemical Tools to Control Multiple Pathogenic Features in Alzheimer’s Disease
- Acc. Chem. Res., Publication Date:October 4, 2021 | https://doi.org/10.1021/acs.accounts.1c00457
- 2021-10
- 생명과학
- 한빛사논문
Key Physicochemical and Biological Factors of the Phase Behavior of Tau
- Chem, Available online 8 October 2020 | https://doi.org/10.1016/j.chempr.2020.09.012
- 2020-10
- 생명과학
- 한빛사논문
Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia
- J. Am. Chem. Soc., Published online 23 April 2020 | https://doi.org/10.1021/jacs.9b13100
- 2020-04
- 생명과학
- 한빛사논문

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