이은우 (한국생명공학연구원, UST)님 | 한빛사연구자 > 한빛사

[Research Highlight] "Good" fats, bad news: HDL-delivered vitamin E shields tumors from ferroptosis

Signal Transduct. Target. Ther., Sep 02 2025, 10 (1) 284 | https://doi.org/10.1038/s41392-025-02373-x

[News & Views] When gut fibroblasts feed epithelial cells to death

The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism.

Nat. Commun., Sep 15 2023, 14 (1) 5728 | https://doi.org/10.1038/s41467-023-41462-9

An integrated view of lipid metabolism in ferroptosis revisited via lipidomic analysis

A new way to create ether lipids

Nat. Chem. Biol., 2023 Mar;19(3):259-260 | https://doi.org/10.1038/s41589-023-01255-z

Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor

Cell Death Differ., Published 04 August 2022 | https://doi.org/10.1038/s41418-022-01047-3

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

Cell Death Dis., Published 04 November 2019 | https://doi.org/10.1038/s41419-019-2061-8

Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer

Proc. Natl. Acad. Sci. USA, First published December 7, 2020 | https://doi.org/10.1073/pnas.2006828117

Identification of MYC as an antinecroptotic protein that stifles RIPK1–RIPK3 complex formation

Proc. Natl. Acad. Sci. USA, First published August 4, 2020 | https://doi.org/10.1073/pnas.2000979117

CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3

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