배은주 (전북대학교 약학대학)님 | 한빛사연구자 > 한빛사

PAK4 in metabolic diseases: regulation by nutrient signals and therapeutic implications

Sirt6 deficiency in mast cells promotes adipose fibroinflammation in obesity through galectin-3 signaling

Nat. Commun., 06 January 2026;17;57(2026) | https://doi.org/10.1038/s41467-025-66040-z

PAK4 phosphorylates cyclin-dependent kinase 2 to promote the G1/S transition during adipogenesis

Cannabidiol reshapes the gut microbiome to promote endurance exercise in mice

PAK4 phosphorylates and inhibits AMPKα to control glucose uptake

p21-activated kinase 4 counteracts PKA-dependent lipolysis by phosphorylating FABP4 and HSL

p21-activated kinase 4 suppresses fatty acid β-oxidation and ketogenesis by phosphorylating NCoR1

Nat. Commun., 2023 Aug 17;14(1):4987 | https://doi.org/10.1038/s41467-023-40597-z

NAD+-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice

Theranostics, Published 2022-4-11 12(7):3316-3328 | https://doi.org/10.7150/thno.69684

Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression

Nat. Commun., Published 04 April 2022 | https://doi.org/10.1038/s41467-022-29472-5

PAK4 inhibition protects against liver ischemia/reperfusion injury: Role of Nrf2 phosphorylation

Hepatology, First published: 02 February 2022 | https://doi.org/10.1002/hep.32384

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