한빛사
>
상위피인용논문
상위피인용논문
- 조회56
Nat. Rev. Bioeng., 29 September 2023 | https://doi.org/10.1038/s44222-023-00102-z
Soft bioelectronics for the management of cardiovascular diseases
Sung-Hyuk Sunwoo 1,2,8, Sang Ihn Han 2,3,4,8, Chan Soon Park 5,8, Jeong Hyun Kim 2, Joanna S. Georgiou 2,3, Seung-Pyo Lee 2,5,6,*, Dae-Hyeong Kim 2,3,7,* & Taeghwan Hyeon 2,3,*
1Medical Research Center, Seoul National University, Seoul, Republic of Korea.
2Center for Nanoparticle Research, Institute for Basic Science (IBS), Seoul, Republic of Korea.
3School of Chemical and Biological Engineering, and Institute of Chemical Processes, Seoul National University, Seoul, Republic of Korea.
4Biomaterials Research Center, Biomedical Research Division, Korea Institute of Science and Technology, Seoul, Republic of Korea.
5Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
6Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
7Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea.
8These authors contributed equally: Sung-Hyuk Sunwoo, Sang Ihn Han, Chan Soon Park.
2Center for Nanoparticle Research, Institute for Basic Science (IBS), Seoul, Republic of Korea.
3School of Chemical and Biological Engineering, and Institute of Chemical Processes, Seoul National University, Seoul, Republic of Korea.
4Biomaterials Research Center, Biomedical Research Division, Korea Institute of Science and Technology, Seoul, Republic of Korea.
5Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
6Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
7Department of Materials Science and Engineering, Seoul National University, Seoul, Republic of Korea.
8These authors contributed equally: Sung-Hyuk Sunwoo, Sang Ihn Han, Chan Soon Park.
*Corresponding authors: correspondence to eung-Pyo Lee, Dae-Hyeong Kim or Taeghwan Hyeon
Abstract
The motions of the heart are regulated by electrophysiological signals, which can be monitored and altered by bioelectronic devices for the diagnosis and treatment of cardiovascular diseases. In particular, soft bioelectronic devices, composed of deformable and conductive materials, can be implanted or designed as wearable devices to enable conformal contact with heart tissue or the skin for real-time and precise diagnosis and treatment. In this Review, we discuss the design and materials of soft bioelectronic devices, highlighting their advantages, as compared with rigid bioelectronic devices, in cardiovascular disease management. We examine the engineering and applications of soft implantable bioelectronics, including cardiac mapping devices, cardiac stimulation devices and mechanically assisting devices, as well as wearable soft bioelectronics, such as blood oxygen saturation sensors, heart monitoring devices and transdermal drug delivery systems. Finally, we outline technical challenges and future opportunities for the clinical application of soft bioelectronic devices, such as a wireless power supply, optogenetic control of cardiac motion, bioadhesives for device–tissue interfaces and artificial intelligence-assisted data analysis.
논문정보
- Review Paper
- 2023년 09월 (BRIC 등록일 2025-08-07)
- 국내 연구진
- 바이오·의료융합 > 바이오센싱 및 나노바이오물질
- 60회 이상 인용된 논문
댓글 작성 로그인
팝업 닫기관련 링크
연구자 키워드
관련분야 연구자보기
소속기관 논문보기
관련분야 논문보기
