최인근 (한림대학교 한강성심병원) | 상위피인용논문 > 한빛사

상위피인용논문

조회65

최인근Ihn-Geun Choi

한림대학교 한강성심병원

Psychiatry Investig., 2012 Jan 17;9(1):8–16 | https://doi.org/10.4306/pi.2012.9.1.8 Alcohol and Cognition in the Elderly: A Review

Jee Wook Kim ^1,2, Dong Young Lee ³, Boung Chul Lee^1,2, Myung Hun Jung ⁴, Hano Kim⁵, Yong Sung Choi ⁶, Ihn-Geun Choi ¹^,2,*

¹Department of Neuropsychiatry, Hallym University Hangang Sacred Heart Hospital, Seoul, Korea.
²Hallym University Burn Institute, Hallym University, Seoul, Korea.
³Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea.
⁴Department of Neuropsychiatry, Hallym University Sacred Heart Hospital, Anyang, Korea.
⁵Department of Neuropsychiatry, Keyo Hospital, Uiwang, Korea.
⁶Department of Neuropsychiatry, St. Andrew's Neuropsychiatric Hospital, Icheon, Korea.

^*Corresponding author: correspondence to Ihn-Geun Choi

Abstract

Consumption of large amounts of alcohol is known to have negative effects, but consumption in smaller amounts may be protective. The effect of alcohol may be greater in the elderly than in younger adults, particularly with regard to cognition. However, the drinking pattern that will provide optimal protection against dementia and cognitive decline in the elderly has not been systematically investigated. The present paper is a critical review of research on the effect of alcohol on cognitive function and dementia in the elderly. Studies published from 1971 to 2011 related to alcohol and cognition in the elderly were reviewed using a PubMed search. Alcohol may have both a neurotoxic and neuroprotective effect. Longitudinal and brain imaging studies in the elderly show that excessive alcohol consumption may increase the risk of cognitive dysfunction and dementia, but low to moderate alcohol intake may protect against cognitive decline and dementia and provide cardiovascular benefits. Evidence suggesting that low to moderate alcohol consumption in the elderly protects against cognitive decline and dementia exists; however, because of varying methodology and a lack of standardized definitions, these findings should be interpreted with caution. It is important to conduct more, well-designed studies to identify the alcohol drinking pattern that will optimally protect the elderly against cognitive decline and dementia.

논문정보

형식Review Paper
게재일2012년 01월 (BRIC 등록일 2025-07-01)
연구진국내 연구진
분야 의약학 > 신경의학
피인용횟수120회 이상 인용된 논문

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