상위피인용논문
- 조회1,129
KAIST
Tong Un Chae1, So Young Choi1, Je Woong Kim, Yoo-Sung Ko, Sang Yup Lee*
Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 Plus Program), BioProcess Engineering Research Center, Institute for the BioCentury, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea
1Both authors contributed equally to this work.
*Corresponding author
Abstract
Metabolic engineering has been playing increasingly important roles in developing microbial cell factories for the production of various chemicals and materials to achieve sustainable chemical industry. Nowadays, many tools and strategies are available for performing systems metabolic engineering that allows systems-level metabolic engineering in more sophisticated and diverse ways by adopting rapidly advancing methodologies and tools of systems biology, synthetic biology and evolutionary engineering. As an outcome, development of more efficient microbial cell factories has become possible. Here, we review recent advances in systems metabolic engineering tools and strategies together with accompanying application examples. In addition, we describe how these tools and strategies work together in simultaneous and synergistic ways to develop novel microbial cell factories.
논문정보
- Review Paper
- 2017년 10월 (BRIC 등록일 2020-07-16)
- 국내 연구진
- 생명과학 > 응용생물화학
- 60회 이상 인용된 논문
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