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한국외국어대학교

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Org. Lett., May 6, 2011, 13 (11), pp 2799–2801 | DOI: 10.1021/ol200967w Ratiometric Fluorescence Imaging of Cellular Glutathione

Abstract

Gun-Joong Kim^†, Kiwon Lee^‡, Hyockman Kwon^‡, and Hae-Jo Kim^†,*

Department of Chemistry^† and Department of Bioscience and Biotechnology^‡, Hankuk University of Foreign Studies, Yongin 449-791, Republic of Korea

^*Correspondence : Hae-Jo Kim

Abstract
A fluorescent probe (1) with a hydrogen bond was designed for the detection of GSH. The probe exhibited a rapid and ratiometric fluorescence response to GSH through a Michael reaction and allowed us to obtain clear cellular images for GSH.

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