연구용제품Bio resource > Cell
AnyGeneRepression : CRISPR/Cas9 -based GeneRepress
제넨메드
- 조회925
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카달로그 NOGEN-2011-003
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원산지KOREA
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생산기업Genenmed Inc.
AnyGeneRepressionTM : a CRISPR/Cas9-based Gene Repression
어떤 유전자에도 적용 가능한
고효율 Gene Repression system!!
- CRISPR/dCas9KRAB system 활용
- 어떤 유전자도 Repression 가능
- 다수의 유전자를 동시에 Repression 가능
- Gene Repression 세포에 외인성 DNA의 형질주입 가능성 제로
1. Notice
- The AnyGeneRepressionTM is an Adenovirus-based CRISPR/dCas9KRAB system
- The AnyGeneRepressionTM is for research use only
- For clinical use or any other purpose, you should obtain a license from Genenmed Inc.
- The AnyGeneRepressionTM utilizes Genenmed’s proprietary pAdBest® system
- As safety consideration, follow the recommended NIH guideline for BSL-2
2. General information
- The AnyGeneRepressionTM comprises an Adenovirus expressing both Target Guide RNA
and dCas9KRAB simultaneously in a single Adenovirus particle
- Unlike shRNA, the AnyGeneRepressionTM represses transcription (termed CRISPRi)
- Adenovirus infects a wide variety of cells and strongly expresses the exogenous genes
in target cells
2) For customers
- Customer should provide the target sequence (20 nucleotide in length)
around the transcription start site of the target gene (see Figure for detail)
- Customer will receive purified Adenovirus (~1x1010 viral particles/ml)
3.Questions
- TEL: 82-2-3474-5800
- E-mail: sales@genenmed.com
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