연구용제품Bio resource > Cell
AnyGeneKI:CRISPR/Cas9-based Gene knock-in
제넨메드
AnyGeneKITM : a CRISPR/Cas9-based Gene Knock-in
어떤 유전자에도 적용 가능한
고효율 Knock-in system!!
- CRISPR/Cas9 system 활용
- 어떤 유전자도 Knock-in 가능
- 다수의 유전자를 동시에 knock-in 가능
- Knock-in 세포에 외인성 DNA의 형질주입 가능성 제로
1. Notice
- AnyGeneKITM, a gene knock-in (KI) service, utilizes CRISPR/Cas9 system
- The knock-in cell lines generated are for research use only (for clinical use or
any other purpose, you should obtain a license from Genenmed Inc.)
2. General information
1) About gene Knock_In
- Gene knock-in can be used for gene knock-out, deletion, insertion, etc
- Gene knock-in is accomplished by two Target Guide RNA/Cas9 vectors
and a knock-in donor vector (three plasmids or three adenoviruses)
- Unlike the plasmid based knock-in, the adenovirus-based knock-in does not leave
(or extremely low probability) an exogenous DNA in the established cell line
2) For customers
- Customer should provide host cell line
- If host cell line needs special culture conditions, extra-charge is requested
- Customer should provide the target sequence (20 nucleotide in length) for gene knock-in
(see Figure for detail)
- Customer should provide the antibody for Western blotting
3.Services
- Plasmid-based knock-in
- Adenovirus-based knock-in
4. Questions
- TEL: 82-2-3474-5800
- E-mail: sales@genenmed.com