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바이오젬스코리아

  • 등록2026.10.03
  • 조회16
Dexamethasone ( GR Agonist ) [ 5000222 ]

Dexamethasone ( GR Agonist ) [ 5000222 ]

본 정보는 "바이오젬스코리아"(으)로 문의 바랍니다.


 

Dexamethasone  

Catalog Number : 5000222  
덱사메타손은 합성 항염증 및 면역 억제 스테로이드입니다.  천연 하이드로코르티손 리간드보다 글루코코르티코이드 수용체에 대해 더 강한 친화력을 가지고 있습니다.  덱사메타손은 성숙한 수지상 세포 분화를 억제하고 인간 중간엽 세포의 분화를 촉진하는 것으로 보고되었습니다. 

 
SIZE  가격 (부가세별도)  제품번호  
500mg  $60.00 
5000222-500mg   
5g  $340.00 
5000222-5g   
  • Download TDS           

  • Soluble in organic solvents such as ethanol or DMSO.   10 mg in 0.2548 mL solvent is 100 mM.   
    Product should be kept at -20°C.    Sterilize with 0.22 µm filter before use.     

   

[ 제품 인용 최신 논문 ]    
  1. Lee Y, Lim KM, Bong H, Lee SB, Jeon TI, Lee SY, Park HS, Kim JY, Song K, Kang GH, Kim SJ, Song M, Cho SG. The Immobilization of an FGF2-Derived Peptide on Culture Plates Improves the Production and Therapeutic Potential of Extracellular Vesicles from Wharton’s Jelly Mesenchymal Stem Cells. Int J Mol Sci. 2024 Oct 4;25(19):10709. doi: 10.3390/ijms251910709. PMID: 39409038; PMCID: PMC11477336.
  2. Brown GE, Han YD, Michell AR, Ly OT, Vanoye CG, Spanghero E, George AL Jr, Darbar D, Khetani SR. Engineered cocultures of iPSC-derived atrial cardiomyocytes and atrial fibroblasts for modeling atrial fibrillation. Sci Adv. 2024 Jan 19;10(3):eadg1222. doi: 10.1126/sciadv.adg1222. Epub 2024 Jan 19. PMID: 38241367; PMCID: PMC10798559.  
  3. Helena GA, Watanabe T, Kato Y, Shiraki N, Kume S. Activation of cAMP (EPAC2) signaling pathway promotes hepatocyte attachment. Sci Rep. 2023 Jul 31;13(1):12352. doi: 10.1038/s41598-023-39712-3. PMID: 37524826; PMCID: PMC10390557.  
  4. Song H, Bucher S, Rosenberg K, Tsui M, Burhan D, Hoffman D, Cho SJ, Rangaswami A, Breese M, Leung S, Ventura MVP, Sweet-Cordero EA, Huang FW, Nijagal A, Wang B. Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids. Nat Commun. 2022 Aug 25;13(1):4878. doi: 10.1038/s41467-022-32473-z. PMID: 36008377; PMCID: PMC9411569.  
  5. Ly OT, Chen H, Brown GE, Hong L, Wang X, Han YD, Pavel MA, Sridhar A, Maienschein-Cline M, Chalazan B, Ong SG, Abdelhady K, Massad M, Rizkallah LE, Rehman J, Khetani SR, Darbar D. Mutant ANP induces mitochondrial and ion channel remodeling in a human iPSC-derived atrial fibrillation model. JCI Insight. 2022 Apr 8;7(7):e155640. doi: 10.1172/jci.insight.155640. PMID: 35393944; PMCID: PMC9057627. 

  

ADDITIONAL INFORMATION  

Applications:  
FA  
Synonyms:  
Decaject, Decameth, Decaspray, Dexasone, Hexadecadrol  
Formulation:  
Crystalline solid  
Chemical Name:  
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one  
Molecular Formula:  

C22H29FO5  

Molecular Weight:  
392.5  
CAS Number  
50-02-2  
Purity:  
≥98%  
Storage Conditions:  
Product should be kept at -20°C.  
References:  

Haynesworth, S. E., Baber, M. A., & Caplan, A. I. (1996). Cytokine expression by human marrow‐derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL‐1α. Journal of cellular physiology, 166(3), 585-592.  

Han, J., Thompson, P., & Beutler, B. (1990). Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway. The Journal of experimental medicine, 172(1), 391-394.  

Larsson, E. L. (1980). Cyclosporin A and dexamethasone suppress T cell responses by selectively acting at distinct sites of the triggering process. The Journal of Immunology, 124(6), 2828-2833.  

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Dexamethasone ( GR Agonist ) [ 5000222 ]

본 정보는 "바이오젬스코리아"(으)로 문의 바랍니다.

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