바이오클론
- 등록2026.01.29
- 조회35
![[Apexbio] EZ Cap™ Cy5 Firefly Luciferase mRNA (5-moUTP)](/app/board/attach/image/1346136_1769650674000.do)
[Apexbio] EZ Cap™ Cy5 Firefly Luciferase mRNA (5-moUTP)
- 분류 시약 > Chemical Reagent
- 브랜드Apexbio
- 원산지USA
- 이메일 bioclone@bioclone.co.kr
- 연락처 02-2690-0058
APExBIO 는 Small molecule, Inhibitor, Peptide 등의 chemical 관련 제품을 직접 생산, 공급하는 브랜드입니다.
APExBIO mRNA Research Solutions
발주 : 매주 금요일 4시
바이오클론(주)는 APExBIO의 한국독점대리점이며,
2015년부터 정부의 화학물질의 등록 및 평가 등에 관한 법률(화평법)에 의해 모든 화학물질을 한국환경공단에
신고, 허가 하에 안전하게 수입 공급하고 있습니다.
한국환경공단 신고허가없이 수입되거나 공식대리점이 아닌 무분별한 수입업자에 공급되어진 화학물질품목은 화평법에 의해 문제소지가 발생할수 있습니다 |
EZ Cap™ Cy5 Firefly Luciferase mRNA (5-moUTP)
Catalog No.
R1010
Background
EZ Cap™Cy5 Firefly Luciferase mRNA (5-moUTP) is a high-performance, dual-reporting mRNA product designed for advanced gene expression and intracellular tracking studies. It combines robust protein expression with sensitive fluorescence detection in a single construct. Firefly Luciferase catalyzes ATP-dependent D-luciferin oxidation and lead to yield chemiluminescence at about 560 nm wavelength. Cy5 (Cyanine-5) is a fluorescent compound with an excitation peak at 646 nm and an emission peak at 662 nm. This ready-to-use mRNA is ideal for real-time tracking of mRNA delivery, optimizing transfection protocols, and dual-modality studies combining bioluminescence imaging with fluorescence-based localization. It serves as a valuable tool in mRNA vaccine development, gene therapy research, and intracellular trafficking assays.
Key features:
Fluorescent Labeling: The mRNA is covalently conjugated with Cy5 dye, enabling direct visualization of mRNA delivery, cellular uptake, and intracellular trafficking using fluorescence microscopy or flow cytometry, without the need for secondary detection steps.
Cap1 Structure:The mRNA incorporates a Cap1 analog at the 5' end, ensuring high translation initiation efficiency, improved stability, and reduced innate immune recognition, leading to stronger and more sustained luciferase expression.
Modified Nucleotides:It contains 5-methoxyuridine (5-moU) modified nucleotides, which decreases immunogenicity, enhances mRNA stability, and increases translational efficiency, resulting in more reliable and reproducible protein yield.
Description
| mRNA Length | 1921 nucleotides |
| Concentration | 1 mg/mL |
| Buffer | 1 mM Sodium Citrate, pH 6.4 |
| Storage | -40°C or below |
| General tips | Dissolve it on ice and take care to prevent RNase contamination degradation. Avoid repeated freezing and thawing as much as possible. Do not vortex. For the first time, it is gently centrifuged and divided into several parts for stand-alone use. Use RNase-free reagents and consumables, using appropriate RNase-free technology. It can not be added to the serum-containing medium until it is mixed with the transfection reagent. |
| Shipping Condition | Ship with dry ice. |
Product Citation
- 1. Shuling Ren, Xinyu Lin, et al. "Redox-Responsive Peptide Coacervates for Enhanced mRNA Delivery and Intracellular Release." ACS Nano. 2025 Dec 26. PMID: 41451635
- 2. Paul Folda, Eric Weidinger, et al. "PEGylation Enhances Colloidal Stability and Promotes Ligand-Mediated Targeting of LAF-Xenopeptide mRNA Complexes." Polymers (Basel). 2025 Nov 9;17(22):2979. PMID: 41304345
- 3. Lijuan Shao, Yi Zhang, et al. "Synthetic efferocytic receptor microglia enhances anti-inflammatory clearance of amyloid-β for AD treatment in mice." Sci Adv. 2025 Jul 11;11(28):eads6613. PMID: 40632863
- 4. Harrison Douglas Lawson, Huy Hoang Nguyen, et al. "Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks." ADVANCED FUNCTIONAL MATERIALS 19 May 2025
- 5. Jade Forrester, Callum G. Davidson, et al. "Low-Cost Microfluidic Mixers: Are They up to the Task?." Pharmaceutics. 2025 Apr 25;17(5):566. PMID: 40430858
mRNA Research Solutions
All of our mRNA products offer:
- Incorporates ARCA (Cap 0) or EZ Cap (Cap 1) into the transcript to increase translation efficiency
- Reduces host cell immune response and enhances stability by incorporating modified nucleotides (5mCTP and ψUTP) and a poly(A) tail
- Degrades the DNA template after RNA synthesis with DNase
- Removes the 5’ triphosphates at the end of the RNA with phosphatase to further reduce innate immune responses in mammalian cells
- Employs a robust clean-up spin column system that delivers high yields of mRNAs that are ready for most downstream applications
Validation:
매주 금요일 4시 발주
자세한 문의사항은 바이오클론으로 연락주세요
Homepage : www.bioclone.co.kr
한국독점대리점 바이오클론㈜
T) 02-2690-0058 F) 02-2690-0397
mRNA
Apexbio
EZ Cap
Cy5
Luciferase
- [Sanguine] Healthy Human Plasma 2026.02.13
- [FuGENE] FuGENE® 4K Transfection Reagent_ 4K-1000 2026.02.13
- [Apexbio] EZ Cap™ Cy5 Firefly Luciferase mRNA (5-moUTP) 2026.02.13
- [NCTC] Clostridium perfringens 2026.02.12
- [Medchemexpress]Human IgG1 kappa, Isotype Control 대조군 2026.02.12
- [medchemexpress]트라스트주맙(바이오시밀러베스트셀러) 2026.02.12
- [NCTC] Enterobacter cloacae 2026.02.11
- [biorbyt] Monkey-derived ELISA Kits 2026.02.11
- Biolegend Maxpar® Ready Purified Antibodies -CyTOF 2026.02.11
- [biorbyt] Lipid Nanoparticles 2026.02.10
