Duke-NUS Medical School
The Signature Research Program in Neuroscience and Behavioral Disorders comprises research groups that investigate molecular, developmental, systems and cognitive neuroscience.
생명공학 분야에서 대학원과정을 수료/졸업하셨거나 졸업을 앞두고 계신분 중 박사후 연구원을 Singapore에 있는 Duke-NUS Medical School에 위치한 저희 연구실에서 모집하고 있습니다. 저희는 여러가지 모델 시스템을 이용해서, 뇌질환의 연인과 치료를 목적으로 연구하고 있으며, 특별히 iPSC에서 제작한 신경세포와 뇌오가노이드를 이용해서 여러가지 뇌질환을 연구하고 있습니다. 대표논문들은 여기서 찾으실 수 있고, https://scholar.google.com.sg/citations?hl=en&user=1qgSl3kAAAAJ&view_op=list_works&sortby=pubdate 항상 새로운 방향과 분야를 선도할 수 있는 재미있는 프로젝트들을 하고 있습니다. 저희 연구실에 관심있으신 분들은 이력서를 email@example.com 로 보내주시기 바랍니다.
Postdoctoral Researcher- Je lab.
The Je lab at Duke-NUS Medical School is seeking a Postdoctoral Scientist to model neural disorders using iPSCs. The successful candidate will have some experience in stem cell biology. They will have a demonstrated aptitude to be a leading author on peer-reviewed publications, provide innovative solutions to research problems, and can apply for fellowship/scholarship awards.
The Je lab focuses on understanding the fundamental mechanisms that lead to neural disorders and identifying new therapeutic targets for these diseases. Induced pluripotent stem cells (iPSC) derived from patient cells, genomics, CRISPR/Cas9 based genome editing, genomics, proteomics, small molecule screens, single-cell analysis, and electrophysiology are all technologies applied to deepen our understanding of uncurable neural disorders (Jo et al., Annals of Neurology, 2021; Cho et al., Nature Comm, 2021; Kwak et al., Stem Cells, 2020, Sun et al., Science, 2019.). For more publications, please refer to-
• Participate in innovative research aimed at understanding the role of genetic aberrations in rare neural disorders (syndromic autism, familial Parkinson’s disease, familial Alzheimer’s diseases, and other rare neural disorders).
• Focus on developing protocols to generate specific subtypes of human-induced neurons and brain organoids with single-cell genomics and functional validation.
• Collaborate with a biologist at Duke-NUS for developing standardized protocols and experimental design.
• Perform data analysis, annotation, protocol (IRB/IACUC/GMAC) preparation, pathway analysis, visualization, and machine-learning-based imaging and data analysis.
• Attend and participate in institutional programs, seminars, and lab meetings.
Ph.D. in cell biology, stem cell biology, neuroscience, chemistry, or other related fields.
Excellent cell culture skills.
Background in hESCs and iPSCs.
Experience in stem cell biology and CRISPR/Cas9 genome editing. CRISPRa or CRISPRi based screening is a plus.
Demonstrated ability to be a leading author in peer-reviewed publications.
Work well in an interdisciplinary team of scientists.
Self-motivated and collaborative.