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[Correspondence]The Ratio of Peripheral Regulatory T Cells to Lox-1+ Polymorphonuclear Myeloid-derived Suppressor Cells Predicts the Early Response to Anti–PD-1 Therapy in Patients with Non–Small Cell Lung Cancer
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Abstract

Immune checkpoint inhibitors (ICIs) have emerged as a promising treatment modality for patients with non-small cell lung cancer (NSCLC). However, ICI monotherapy has a relatively low response rate (approximately 20-50% in patients with NSCLC) (1), and consequently it is important to develop predictive biomarkers of response to inform clinical decisions regarding ICI use. Although PD-L1 expression on tumor cells is currently used as a predictive determinant for anti-PD-1 therapy responses, the accuracy of this test is relatively poor. Therefore, better predictive biomarkers for anti-PD-1 therapy in patients with NSCLC are needed.

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- Çü½Ä: Correspondence
- °ÔÀçÀÏ: 2019³â 01¿ù (BRIC µî·ÏÀÏ 2019-02-01)
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- ºÐ¾ß: Medicine
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Medicine

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Google (by Hye Ryun Kim)
Pubmed (by Hye Ryun Kim)
ÇÁ¸®¹Ì¾ö BioÀÏÁ¤ BioÀÏÁ¤ ÇÁ¸®¹Ì¾ö ¾È³»
2019 Korean Researchers¡¯ Night in AACR Âü°¡ ½Åû ¾È³» (¹Ì±¹ ¾ÖƲ·£Å¸)
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»çÀüÁ¢¼ö: ~2019.02.20
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