[Preview]Bacterial Protein Reshapes Host Defense toward Antiviral Responses
Authors and Affiliations
In this issue of Molecular Cell, Penn et al. (2018) report the protein interactome between Mycobacterium tuberculosis ( Mtb) secreted effectors and macrophage cytosolic proteins. This Resource reveals that the interaction of Mtb effector LpqN with host CBL counteracts antibacterial defense but causes a reciprocal enhancement of antiviral defense.