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[Preview]Bacterial Protein Reshapes Host Defense toward Antiviral Responses
 Authors and Affiliations  Authors and Affiliations
Hyungjin Eoh1,* and Jae U. Jung1
1Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
*Correspondence : Hyungjin Eoh
Abstract
In this issue of Molecular Cell, Penn et al. (2018) report the protein interactome between Mycobacterium tuberculosis ( Mtb) secreted effectors and macrophage cytosolic proteins. This Resource reveals that the interaction of Mtb effector LpqN with host CBL counteracts antibacterial defense but causes a reciprocal enhancement of antiviral defense.
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